Donkey Secondary Antibodies
Jackson Immuno Research Labs Alkaline Phosphatase-AffiniPure Donkey Anti-Sheep IgG (H+L)
Alkaline Phosphatase-AffiniPure Donkey Anti-Sheep IgG (H+L)
LICOR IRDye 680RD Donkey anti-Goat IgG Secondary Antibody (0.1 mg)
Immunogen: Goat IgG | Applications: IRDye 680RD Donkey anti-Goat IgG Secondary Antibody is highly recommended for Western Blot, In-Cell Western Assay, On-Cell Western Assay, Protein Array, Immunohistochemistry, Small Animal Imaging, Microscopy, 2D Gel Detection, and Tissue Section Imaging | Formulation: IRDye 680RD Secondary Antibodies are supplied as purified immunoglobulin conjugates, lyophilized in phosphate-buffered saline, pH 7.4. Protect from light. Store at 4 °C prior to reconstitution. Each vial contains 10 mg/mL BSA (free of IgG and protease) as a stabilizer and 0.01% sodium azide as a preservative, after reconstitution. Concentration is 1.0 mg/mL when reconstituted as directed. Refer to the pack insert for details on reconstitution.
Jackson Immuno Research Labs Alkaline Phosphatase-AffiniPure Donkey Anti-Mouse IgM µ Chain Specific (min X Hu Bov Hrs Rat Sr Prot)
Alkaline Phosphatase-AffiniPure Donkey Anti-Mouse IgM µ Chain Specific (min X Hu Bov Hrs Rat Sr Prot)
Jackson Immuno Research Labs Biotin-SP-AffiniPure Donkey Anti-Mouse IgM µ Chain Specific
Biotin-SP-AffiniPure Donkey Anti-Mouse IgM µ Chain Specific
Biotium Tenascin C (Stromal Marker for Epithelial Malignancy)(TNC/3635), CF647 conjugate, 0.1mg/mL
In Western blotting, this antibody reacts with two bands of ~MW of 210 kDa and 300 kDa, identified as two isoforms of Tenascin C. Specificity of this MAb is validated by sequential immunoprecipitation with a PAb against Tenascin C. Tenascin C is a multifunctional, disulfide-linkedhexameric extracellular matrix glycoprotein expressed in association with mesenchymal epithelial interactions during development and in the neo-vasculature and stroma of undifferentiated tumors. In adults, it is restricted to certain epithelial-stromal interfaces and increases markedly in hyper-proliferative diseases and in stroma of many neoplasms, including gliomas, breast, squamous and lung carcinomas. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue
Biotium AKT1 (Prognostic Marker for Neuroendocrine Tumors)(rAKT1/2491), CF647 conjugate, 0.1mg/mL
This antibody recognizes a protein of 62 kDa, which is identified as AKT1. The serine/threonine kinase Akt family contains several members, including Akt1 (also designated PKB or RacPK), Akt2 (also designated PKBbeta or RacPK-beta) and Akt3 (also designated PKB-gamma or thymoma viral proto-oncogene 3), which exhibit sequence homology with the protein kinase A and C families and are encoded by the c-Akt proto-oncogene. All members of the Akt family have a Pleckstrin homology domain. Akt1 and Akt2 are activated by PDGF stimulation. This activation is dependent on PDGFR-beta tyrosine residues 740 and 751, which bind the subunit of the phosphatidylinositol 3-kinase (PI 3-kinase) complex. Activation of Akt1 by insulin or insulin-growth factor-1 (IGF-1) results in phosphorylation of both Thr 308 and Ser 473. Akt proteins become phosphorylated and activated in insulin/IGF-1-stimulated cells by an upstream kinase(s), and the activation of Akt1 and Akt2 is inhibited by the PI kinase i
Biotium MLH1 (MutL Homolog 1)(MLH1/1324), CF647 conjugate, 0.1mg/mL
This MAb recognizes a protein of 83 kDa, identified as MLH1. Defects in MLH1 are the cause of hereditary non-polyposis colorectal cancer type 2 (HNPCC2). Heterodimerizes with PMS2 to form MutL alpha, a component of the post-replicative DNA mismatch repair system (MMR). DNA repair is initiated by MutS alpha (MSH2-MSH6) or MutS beta (MSH2-MSH6) binding to a dsDNA mismatch, then MutL alpha is recruited to the heteroduplex. Assembly of the MutL-MutS-heteroduplex ternary complex in presence of RFC and PCNA is sufficient to activate endonuclease activity of PMS2. It introduces single-strand breaks near the mismatch and thus generates new entry points for the exonuclease EXO1 to degrade the strand containing the mismatch. DNA methylation would prevent cleavage and therefore assure that only the newly mutated DNA strand is going to be corrected. MutL alpha (MLH1-PMS2) interacts physically with the clamp loader subunits of DNA polymerase III, suggesting that it may play a role to recr
Jackson Immuno Research Labs Brilliant Violet™ 421-AffiniPure Donkey Anti-Sheep IgG (H+L) (min X Ck GP Sy Hms Hrs Hu Ms Rb Rat Sr Prot)
Brilliant Violet™ 421-AffiniPure Donkey Anti-Sheep IgG (H+L) (min X Ck GP Sy Hms Hrs Hu Ms Rb Rat Sr Prot)
Jackson Immuno Research Labs 4 nm Colloidal Gold-AffiniPure Donkey Anti-Guinea Pig IgG (H+L) (min X Bov Ck Gt Sy Hms Hrs Hu Ms Rb Rat Shp Sr Prot) (LM Grade)
4 nm Colloidal Gold-AffiniPure Donkey Anti-Guinea Pig IgG (H+L) (min X Bov Ck Gt Sy Hms Hrs Hu Ms Rb Rat Shp Sr Prot) (LM Grade)
Jackson Immuno Research Labs Fluorescein (FITC)-AffiniPure Donkey Anti-Sheep IgG (H+L) (min X Ck GP Sy Hms Hrs Hu Ms Rb Rat Sr Prot)
Fluorescein (FITC)-AffiniPure Donkey Anti-Sheep IgG (H+L) (min X Ck GP Sy Hms Hrs Hu Ms Rb Rat Sr Prot)
Jackson Immuno Research Labs Cy™3 AffiniPure Donkey Anti-Guinea Pig IgG (H+L), .5mg
Cy3-AffiniPure Donkey Anti-Guinea Pig IgG (H+L) (min X Bov,Ck,Gt,Sy Hms,Hrs,Hu,Ms,Rb,Rat,Shp Sr Prot)